SEASLogo
NeedlemanLabImageNeedlemanLabName2
Home Research Publications People Available Positions
 
   

Publications

Daniel J. Needleman, Yangqing Xu, Tim Mitchison, Fluorescence Correlation Imaging: Massively Parallel Fluorescence Correlation Spectroscopy. In Preparation.

Daniel J. Needleman, Aaron Groen, Ryoma Ohi, Tom Maresca, Leonid Mirny, Tim Mitchison, Single Molecule Measurements Reveal Microtubule Polymerization Dynamics in the Metaphase Spindle. Submitted.

Martin Wuehr, Yao Chen, Sophie Dumont, Aaron Groen, Daniel J. Needleman, Adrian Salic, Timothy J. Mitchison, Evidence for an Upper Limit to Mitotic Spindle Length. Current Biology, 2008, 18, 1256-1261

Aaron C. Groen, Daniel J. Needleman, Clifford Brangwynne, Christain Gradinaru, Brandon Fowler, Ralph Mazitschek, Timoth J. Mitchison, A Novel Small-Molecule Inhibitor Reveals a Possible Role of Kinesin-5 in Anastral Spindle-Pole Assembly. Journal of Cell Science, 2008, 121, 2293-2300

Daniel J. Needleman, Plasmid Segregation: Is a Total Understanding within Reach? Current Biology, 2008, 18, R212-R214

Uri Raviv, Daniel J, Needleman, Kai Ewert, Cyrus R. Safinya, Hierarchical Bionanotubes Formed by the Self Assembly of Microtubules with Cationic Membranes or Polypeptides. Journal of Applied Crystallography. 2007, 40, s83-s87.

Uri Raviv, Toan Nguyen, Rouzbeh Ghafouri, Daniel J, Needleman, Youli Li, Herbert P. Miller, Leslie Wilson, Robijn F. Bruinsma, Cyrus R. Safinya, Microtubule Protofilament Number is Modulated in a Step-Wise Fashion by the Charge Density of an Enveloping Layer. Biophysical Journal. 2007, 92, 278-287.

Cyrus R. Safinya, Kai Ewert, Ayesha Ahmad, Heather M. Evans, Uri Raviv, Daniel J. Needleman, Alison J. Lin, Nele L. Slack, Cyril George. Cationic Liposome-DNA Complexes: From Liquid Crystal Science to Gene Delivery Applications. Philosophical Transactions of the Royal Society A, 2006, 364, 2573-2596.

Uri Raviv, Daniel J. Needleman, Cyrus R. Safinya, Cationic Membranes Complexed with Oppositely Charged Microtubules: Hierarchical Self-Assembly Leading to Bio-Nanotubes. Journal of Physics: Condensed Matter, 2006, 18, S1271-S1279.

Daniel J. Needleman, Jayna B. Jones, Uri Raviv, Miguel A. Ojeda-Lopez, Herbert P. Miller, Youli Li, Leslie Wilson, Cyrus R. Safinya, Supramolecular Assembly of Biological Molecules Purified from Bovine Nerve Cells: from Microtubule Bundles and Necklaces to Neurofilament Networks. Journal of Physics: Condensed Matter, 2005, 17, S3225-S3230.

Daniel J. Needleman, Miguel Ojeda-Lopez, Uri Raviv, Kai Ewert, Herbert P. Miller, Leslie Wilson, Cyrus R. Safinya, Radial Compression of Microtubules and the Mechanism of Action of Taxol and Associated Proteins. Biophysical Journal, 2005, 89, 3410-3423.

Uri Raviv, Daniel J. Needleman, Miguel Ojeda-Lopez, Herbert P. Miller, Leslie Wilson, Cyrus R. Safinya, Cationic Liposome-Microtubule Complexes: Pathways to the Formation of Two-State Lipid-Protein Nanotubes with Open or Closed Ends. Proceedings of the National Academy of Sciences, Track II, August 2005, 102, 11167-11172

Daniel J. Needleman, Miguel Ojeda-Lopez, Uri Raviv, Herbert P. Miller, Leslie Wilson, Cyrus R. Safinya, Higher Order Assembly of Microtubules by Counter-ions: From Hexagonal Bundles to Living Necklaces. Proceedings of the National Academy of Sciences, Track II, November 2004, 101, 16099-16103

Daniel J. Needleman, Miguel Ojeda-Lopez, Uri Raviv, Kai Ewert, Jayna B. Jones, Herbert P. Miller, Leslie Wilson, Cyrus R. Safinya, Microtubule Buckling and Bundling Under Osmotic Stress: A Synchrotron X-ray Diffraction Study Probing Inter-Protofilament Interactions. Physical Review Letters, November 2004, 93, 198104

Deborah K. Fygenson, Daniel J. Needleman, Kim Sneppen, Variability Based Sequence Alignment Identifies Residues Responsible for Functional Differences in a and b Tubulin. Protein Science, January 2004, 13, 25-31

Daniel J. Needleman, Paul Tiesinga, Terrence J. Sejnowski, Collective Enhancement of Precision in Networks of Coupled Oscillators. Physica D, July 2001, 155, 324-336

Stephen Monks, Daniel J. Needleman, Christopher Miller, Helical Structure and Packing Orientation of the S2 Segment in the Shaker K+ Channel. Journal of General Physiology, March 1999, 113, 415-423

Footer1Footer2
spacerHarvard School of Engineering and Applied Sciences | Molecular and Cellular Biology | FAS Center for Systems Biology
spacerNeedleman Laboratory, 365.10 Northwest Labs, 52 Oxford St, Cambridge MA 02138
Needleman Home Page